Recently my partner got a Samsung Galaxy Note 10.1 and while I was interested in his new toy, I didn't actually think I would personally get any use out of it. How wrong I was! For starters it is easier and lighter to use when I am lying down, as I found out while I was horizontal with my latest ear infection. But now he has bought an even better treat that has made things even better for me!
What he bought is this flexible arm thing which clips onto the back of the bed (the picture below actually doesn't do it much justice) What you can do is clip this onto the back of the bed (or a bed side table) and bend the arm so the tablet hangs above your head. This means that my arms and hands do not ache after a little while, as I no longer need to use them. I can watch videos online and I even played a game like this. Also, because the arm is flexible, I can move to a comfortable position and adjust the position of the tablet to match.
The clamp that attaches to the back of the bed is adjustable and extends up to 5cms, and the part that attaches to the tablet is also adjustable and I even used it with the Samsung Galaxy Note in it's tablet case.
I wouldn't recommend this if you intend to actually be tapping away at your tablet for an extended time, because your tablet will bob about due to the flexible arm it is attached to. Also, once it is attached to your bed, I would suggest that you leave it attached there, rather than repeated removing and reattaching. But if you're anything like me, this shouldn't be a problem.
This is one of those things that is just so simple and inexpensive but makes a world of difference to an ME sufferer like me.